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Ancient polymorphism and functional variation in the primate MHC-DQA1 5′ cis-regulatory region
Dagan A. Loisel, Matthew V. Rockman, Gregory A. Wray, Jeanne Altmann and Susan C. Alberts
Dagan A. Loisel
Matthew V. Rockman
Gregory A. Wray
Jeanne Altmann
Loisel et al. 10.1073/pnas.0607662103. |
Supporting Information
Files in this Data Supplement:
Supporting Table 1Supporting Figure 4
Supporting Table 2
Supporting Figure 4
Fig. 4. Alignment of 47 unique DQA1 proximal promoter haplotypes from nine primate species. Sequence names are composed of the first two letters of the genus and species names. Numbering above sequence corresponds to location upstream of translation start site (8-bp insertion at -22 in Pacy 02 was not included in numbering). Periods indicate identity with Hosa 01. Dashes indicate insertion/deletion polymorphism. Known transcription factor binding sites are shaded.